So far have heard from at least one other player that he also suddenly had smart cast enabled. This can really mess up your earlygame so check it before minions spawn.
I found out the hard way during a lvl 3 gank on vi in my first ranked of the day that smartcast was turned on. When i entered the game my chatscale was different so i checked those settings but missed that smartcast was turned on (on vi your w and e have no difference, and my smiteclicks are so fast i did not notice before i hit lvl 3 and went for a gank). This led to horrible gank since q failed and the laner ragequitted. Bye LP. Dont be like me, doublecheck when the game starts if your settings are normal.