I don't know about higher elo's, but as of right now, in a mid-elo range (plat 2), the one condition that wins games is whether your bot lane is ahead. When I'm playing mid, and I'm farming, the moment I hear from bot lane "an ally has been slain", followed by "enemy double kill", I already know that from that moment, the game is already over, and there is nothing you can do to return. Best part? Because of turret plating, not only are they ahead by two kills, they double down on it by getting 3-4 plates, which basically makes it actually 2.5-3.5 kills, instead of just two. If the jungler comes, that'll probably rid the turret of all its' plates, if not destroying the tower altogether.