I have been playing this game for years and now i want to main vayne, haven't played her for a while and i don't know much about her actual op builds and runes.
If you ask me i would use this runes:
Press the attack + triumph + alacrity and coup de grace.
++ Celerity ++ Gathering storm
And i would use guinsoo since it's the best item for Vayne in the game (personal opinion)
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