What should I build for my next rune page?

So far I have 4 pages; AP: ap quins and glyphs, hp seals and magic pen marks AD speed: attack speed quins, ad marks, mr glyphs and armour seals AD dam: ad quins, armour pen marks, mr glyphs and armour seals Hybrid: ad quins, ad marks, mr glyphs and armour seals Now I have bought a 5th page, what should I build in it?
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