Mouse stuttering in League

Hello,I have been playing League from season 4,and I have an issue that makes the game almost unplayable.Two weeks ago,my mouse started stuttering every minute.This problem is not visible in some other games.I have no problems with Chrome too.I tried to update drivers.I tried Mark`s fix for mouse.I tried uninstalling Realtek audio drivers.I tried closing out almost every app.I just can find a solution.I was Googling around the internet but i found nothing.Help me please.Should I buy a new mouse?Btw i have Windows 10 Enterprise.
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