Odd skillshot issue

Hey guys, i need some help here! Recently, i have been faced with an issue pretty new yo me in LoL, and i have played for many years... My skillshots tend to go the direct oppersite direction of what i fire em, unless i am overdoing my mouse placement. Am I the only one with this issue? I find it rather annoying, and I do not think it is my mouse, since i can play other games perfectly fine! Please help!
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