What should I do with REALLY inexperienced players in ranked?

I started playing my placement matches this season, and I am surprised, I am asking about the people who do not even understand draft pick, can only play 1 champion, which they feed with? I try my best to fill, but sometimes even that doesn't help, I really don't know, they don't even know their kits, sometimes no runes? So what should I do?
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